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Search Results for " LY 2801653 Dihydrochloride "

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カタログ番号 製品名 別名 ターゲット
T15808 Merestinib dihydrochloride LY2801653 dihydrochloride ROCK
Merestinib dihydrochloride is an effective and orally bioavailable c-Met inhibitor (Ki=2 nM). It has anti-tumor activities and also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK...
T3455 Merestinib LY2801653 Discoidin Domain Receptor (DDR) , FLT , c-Met/HGFR , ROS , ROS Kinase
Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity. Merestinib electively binds to c-Met, thereby inhibiting c-Met phosph...